What is L-Isoleucine?

L-Isoleucine is an essential amino acid and is part of the three "branched chain amino acids" (BCAA) - the other two being L-Leucine and L-Valine. This amino cannot be manufactured in the body, and needs to be supplied in the diet, and was first isolated in 1904 from fibrin. L-Isoleucine, together with the other two branched-chain-amino-acids, promotes muscle recovery after physical exercise and on its own it is needed for the formation of hemoglobin as well as assisting with regulation of blood sugar levels as well as energy levels. It is also involved in blood-clot formation.

Who needs it and what are some symptoms of deficiency?

L-Isoleucine is an essential amino acid. Therefore, everyone needs L-Isoleucine to maintain basic health. Symptoms of deficiency may mimic the symptoms of hypoglycemia.

How much should be taken? Are there side effects?

Supplemental L-isoleucine should always be taken with a correct balance of the other two branched-chain amino acids, L-Leucine and L-valine: approximately 2 milligrams of L-Leucine for each 1 milligram of L-Valine and L-Isoleucine. A nutritional conflict might occur with L-Isoleucine and L-Valine if they are not taken in a well-balanced portion (1-to-1).